III. Department of Pharmacology & Therapeutics (PL)
The Department is focusing upon the interaction of drugs and other chemicals with biological systems including individual molecules , cells , tissues , organ systems , and whole individuals.
The department also enables undergraduate students to acquire skills necessary to work in various aspects of biopharmaceutical areas as well as to be engaged in research .
Courses Offered or Supervised by Department of Pharmacology and Therapeutics (PL) : Pharm D – (New Bylaw 2019)
Required courses:
| Required Courses | |||||||||
| Course Title | Cell Biology | ||||||||
| Course Code | PLD 101 | Credit Hours | 2 | Lecture | 2 | Tutorial | 1 | Practical | 0 |
| Course Description: | |||||||||
| The course aims at studying the structure and function of prokaryotic and eukaryotic cells. In this course study will include many different areas of cellular biology involving: the synthesis and function of macromolecules such as DNA and RNA; control of gene expression; membrane and organelle structure and function; bioenergetics; and cellular communication, transformation; transport, receptors, and cell signaling; the cytoskeleton, the extracellular matrix, and cell movements. | |||||||||
| Course Title | Anatomy and Histology | ||||||||
| Course Code | PLD 102 | Credit Hours | 3 | Lecture | 2 | Tutorial | 0 | Practical | 2 |
| Course Description: | |||||||||
| This course aims to provide the students with knowledge concerning the appropriate functions of cells, tissues, organs and body system. The course also enables the student to integrate physiological data and mechanisms with ongoing taught sciences: anatomy and histology. Histology part includes cytology, epithelium, C.T., blood, muscle, vascular, lymphatic, respiratory, gastrointestinal and endocrine systems. Anatomy part includes introduction to human anatomy, tissues of the body, skeletal system, articular system, muscular system, digestive system, cardiovascular, respiratory system, lymphatic system, urinary system, genital system, nervous and endocrine systems. | |||||||||
| Course Title | Psychology | ||||||||
| Course Code | PLD 103 | Credit Hours | 1 | Lecture | 1 | Tutorial | 1 | Practical | 0 |
| Course Description: | |||||||||
| The course introduces different principles, theories and vocabulary of psychology as a science. The course also aims to provide students with basic concepts of social psychology, medical sociology and interpersonal communication which relate to the pharmacy practice system that involves patients, pharmacists, physicians, nurses and other health care professionals. | |||||||||
| Course Title | Physiology and Pathophysiology | ||||||||
| Course Code | PLD 201 | Credit Hours | 3 | Lecture | 2 | Tutorial | 1 | Practical | 2 |
| Course Description: | |||||||||
| Physiology :Introduction to body water, homeostasis, transport of materials, nervous systems, neuron structure and function, cardiovascular system, blood, respiratory cycle, gastrointestinal, reproductive, and renal systems, endocrine glands and body temperature regulation.Pathophysiology: Introduction to pathophysiology, cell injury, inflammation and immune response, autonomic nervous system in health and disease, endocrine disorders, pancreatic disorders, fluid and electrolyte imbalance, vascular and haematological disorders, disease of urinary, pulmonary and digestive systems. | |||||||||
| Course Title | Pathology | ||||||||
| Course Code | PLD 202 | Credit Hours | 2 | Lecture | 2 | Tutorial | 1 | Practical | 0 |
| Course Description: | |||||||||
| The main aim of pathology course is to provide the second year student with knowledge and skills for common diseases affecting body organs and system. It helps the student to understand the causes (etiology) of disease, the mechanisms of its development (pathogenesis) and the associated alterations of structure (morphologic changes) and function (clinical manifestations and complications) to be able to determine the most likely diagnosis of the disease. | |||||||||
| Course Title | Biochemistry I | ||||||||
| Course Code | PLD 203 | Credit Hours | 3 | Lecture | 2 | Tutorial | 0 | Practical | 2 |
| Course Description: | |||||||||
| Proteins (protein structure, biologically important peptides – fate of proteins) – Amino acids as precursors for biosynthesis of biomolecules (e.g. neurotransmitters, nucleotides, …) – Carbohydrates (glycoproteins and proteoglycans – glucose transporters) – Lipids (physiologically important lipid molecules – cholesterol and steroids – lipoprotein metabolism) – Enzymology (enzyme kinetics – regulation – enzyme inhibitors as drugs) – Hemoglobin and porphyrins (Hb derivatives and types– metabolism of Hb and regulation) – Biological oxidation and ATP synthesis – Clinical correlations. | |||||||||
| Course Title | Biochemistry II | ||||||||
| Course Code | PLD 301 | Credit Hours | 3 | Lecture | 2 | Tutorial | 0 | Practical | 2 |
| Course Description: | |||||||||
| Energy production from dietary fuels (carbohydrates, lipids and proteins) –Integration of metabolism (Feed/fast cycle – diabetes mellitus – obesity) – Nitrogen metabolism and nitrogen balance – Hormonal regulation of metabolism – Inborn errors of metabolism – Free radicals and antioxidants. | |||||||||
| Course Title | Pharmacology I | ||||||||
| Course Code | PLD 302 | Credit Hours | 3 | Lecture | 2 | Tutorial | 0 | Practical | 2 |
| Course Description: | |||||||||
| The general principles of pharmacology are presented; such as pharmacokinetics, pharmacodynamics, receptor theory, drug interaction and principle of therapeutics. This course integrates principles of pharmacology with conceptual knowledge of physiology and pathophysiology to disease processes regarding the autonomic, neuromuscular and autacoids. | |||||||||
| Course Title | Pharmacology II | ||||||||
| Course Code | PLD 303 | Credit Hours | 3 | Lecture | 2 | Tutorial | 0 | Practical | 2 |
| Course Description: | |||||||||
| This course integrates principles of pharmacology with conceptual knowledge of physiology and pathophysiology disease processes regarding drugs acting on cardiovascular systems, central nervous system, renal, gastro-intestinal tract, pulmonary systems and hematologic disorders. Antihyperlipidemic drugs are also included. | |||||||||
| Course Title | Pharmacology III | ||||||||
| Course Code | PLD 401 | Credit Hours | 2 | Lecture | 2 | Tutorial | 1 | Practical | 0 |
| Course Description: | |||||||||
| This course integrates principles of pharmacology with conceptual knowledge of physiology and pathophysiology disease processes regarding drugs acting on endocrine system. Chemotherapeutic drugs including antimicrobials, anticancer and immunosuppressant are within the scope of the course. Stem cell therapy is also included. The anti-inflammatory, analgesics as well as gout treatments are also included. | |||||||||
| Course Title | Clinical Biochemistry | ||||||||
| Course Code | PLD 402 | Credit Hours | 3 | Lecture | 2 | Tutorial | 0 | Practical | 2 |
| Course Description: | |||||||||
| Biochemical/pathophysiological changes and laboratory diagnostic markers for disorders of (Endocrine glands – renal function – hepatic function –plasma proteins and lipoproteins) – Clinical enzymology and myocardial infarction – Electrolytes, blood gases and acid-base balance – Handling, preservation, storage and analysis of biological samples – Homeostasis and biochemical aspects of hematology and blood analysis – Urine analysis – Tumor markers – Recent diagnostic biomarkers. | |||||||||
| Course Title | Toxicology and Forensic chemistry | ||||||||
| Course Code | PLD 403 | Credit Hours | 3 | Lecture | 2 | Tutorial | 0 | Practical | 2 |
| Course Description: | |||||||||
| This course provides basics and concepts of toxicology including the mechanism of toxicity, target organ and treatment of toxicity.Toxic groups including heavy metals, toxic gases, animal, plant and marine poisons, pesticides and radiation hazards are covered. Environmental, occupational, reproductive and genetic toxicology as well as drug abuse are included. Postmortem sampling for detection of poisons, methods of detection, interpretation of results and writing of a report are also covered. | |||||||||
| Course Title | Drug interaction | ||||||||
| Course Code | PLD 501 | Credit Hours | 2 | Lecture | 2 | Tutorial | 1 | Practical | 0 |
| Course Description: | |||||||||
| The course is shared between 2 departments: Pharmacology & Pharmacy Practice. This course provides the knowledge and skills enabling them to develop professional competencies in the recognition and discussion of the pharmacological aspects of drug-drug, drug-chemical, drug-herb or drug-food interactions and their clinical significance as well as the application of that knowledge to minimize the risk and outcome of interactions. It covers different types of drug interaction including pharmaceutical interactions, pharmacokinetic interactions, pharmacodynamic interactions, alcohol and smoking drug interactions, CNS drug interactions, interactions of cardiovascular acting drugs, interactions of anticoagulants, interactions of antimicrobials, interactions of immune-based therapies, interactions of hormones, and drug-disease interactions. | |||||||||
| Course Description: | |||||||||
| Course Title | First Aid | ||||||||
| Course Code | PLD 502 | Credit Hours | 1 | Lecture | 1 | Tutorial | 1 | Practical | 0 |
| Basic life support, bleeding, shock, medical emergencies, poisoning, bones and joints, soft tissue injuries, rescue and transportation | |||||||||
| Elective Courses | |||||||||
| Course Title | Pharmacotherapeutics for Special Population | ||||||||
| Course Code | PLD E01 | Credit Hours | 2 | Lecture | 1 | Tutorial | 2 | Practical | 0 |
| Course Description: | |||||||||
| This course aimed to promote health, prevent and treat diseases in pediatric- geriatric aged group in addition to drug therapy for pregnant and lactating patients. | |||||||||
| Course Title | Addiction and Drug Abuse | ||||||||
| Course Code | PLD E02 | Credit Hours | 2 | Lecture | 1 | Tutorial | 2 | Practical | 0 |
| Course Description: | |||||||||
| This course deals with the socio-psychological, biological, genetic and pharmacological aspects of the problem and strategies for prevention and treatment. | |||||||||
| Course Title | Sustainability in Therapeutics | ||||||||
| Course Code | PLD E03 | Credit Hours | 2 | Lecture | 1 | Tutorial | 2 | Practical | 0 |
| Course Description: | |||||||||
| This course covers the different challenges influencing the environment including climate change and pollution. This course also includes the different aspects of sustainability. | |||||||||
| Course Title | Molecular Therapeutics | ||||||||
| Course Code | PLD E04 | Credit Hours | 2 | Lecture | 1 | Tutorial | 2 | Practical | 0 |
| Course Description: | |||||||||
| This course involves a wide range of new molecular therapies such as simple protein replacement therapy, gene augmentation therapy, antisense therapy, stem cells therapy and advanced therapies of cancer. It focuses on the new in the clinical trials of stem cell therapy that considered one of the important types of future medicine. Also, it provides knowledge about the advanced molecular diagnosis and therapy of cancer. | |||||||||
| Course Title | Complementary and Alternative Medicine | ||||||||
| Course Code | PLD E05 | Credit Hours | 2 | Lecture | 1 | Tutorial | 2 | Practical | 0 |
| Course Description: | |||||||||
| The course includes different types of complementary / alternative medicines, such as herbal medicines, homeopathic drugs, aromatherapy, and naturopathy with other nutritional supplements, energy therapy, hydrotherapy, oxygenation therapy and life style intervention in chronic diseases | |||||||||
Pharm-D (Clinical Pharmacy) – (New Bylaw 2019) :
| Required Courses | |||||||||
| Course Title | Cell Biology | ||||||||
| Course Code | PLC 101 | Credit Hours | 2 | Lecture | 2 | Tutorial | 1 | Practical | 0 |
| Course description: | |||||||||
| The course aims at studying the structure and function of prokaryotic and eukaryotic cells. In thiscourse study will include many different areas of cellular biology involving: the synthesis and function of macromolecules such as DNA and RNA; control of gene expression; membrane and organelle structure and function; bioenergetics; and cellular communication, transformation; transport, receptors, and cell signaling; the cytoskeleton, the extracellular matrix, and cell movements. | |||||||||
| Course Title | Anatomy and Histology | ||||||||
| Course Code | PLC 102 | Credit Hours | 3 | Lecture | 2 | Tutorial | 0 | Practical | 2 |
| Course description: | |||||||||
| This course aims to provide the students with knowledge concerning the appropriate functions of cells, tissues, organs and body system. The course also enables the student to integrate physiological data and mechanisms with ongoing taught sciences: anatomy and histology.Histology part includes cytology, epithelium, C.T., blood, muscle, vascular, lymphatic, respiratory, gastrointestinal and endocrine systems. Anatomy part includes introduction to human anatomy, tissues of the body, skeletal system, articular system, muscular system, digestive system, cardiovascular, respiratory system, lymphatic system, urinary system, genital system, nervous and endocrine systems. | |||||||||
| Course Title | Psychology | ||||||||
| Course Code | PLC 103 | Credit Hours | 1 | Lecture | 1 | Tutorial | 1 | Practical | 0 |
| Course description: | |||||||||
| The course introduces different principles, theories and vocabulary of psychology as a science. The course also aims to provide students with basic concepts of social psychology, medical sociology and interpersonal communication which relate to the pharmacy practice system that involves patients, pharmacists, physicians, nurses and other health care professionals. | |||||||||
| Course Title | Biochemistry I | ||||||||
| Course Code | PLC 201 | Credit Hours | 3 | Lecture | 2 | Tutorial | 0 | Practical | 2 |
| Course description: | |||||||||
| Structure of proteins – Biologically active peptides – Protein turnover – Amino acids as precursors for biosynthesis of biomolecules (e.g. neurotransmitters –nucleotides, …) – Structurally and physiologically important lipids – Carbohydrates and connective tissue – Enzymes (theories of enzyme action – enzyme kinetics – inhibition and regulation of enzyme activity – clinical correlations) – The structure and function; fat soluble vitamins, water soluble vitamins , minerals, nucleic acids. | |||||||||
| Course Title | Physiology and pathophysiology | ||||||||
| Course Code | PLC 202 | Credit Hours | 2 | Lecture | 2 | Tutorial | 1 | Practical | 0 |
| Course description: | |||||||||
| Physiology :Introduction to body water, homeostasis, transport of materials, nervous systems, neuron structure and function, cardiovascular system, blood, respiratory cycle, gastrointestinal, reproductive, and renal systems, endocrine glands and body temperature regulation.Pathophysiology: Introduction to pathophysiology, cell injury, inflammation and immune response, autonomic nervous system in health and disease, endocrine disorders, pancreatic disorders, fluid and electrolyte imbalance, vascular and haematological disorders, disease of urinary, pulmonary and digestive systems. | |||||||||
| Course Title | Basic Pharmacology | ||||||||
| Course Code | PLC 203 | Credit Hours | 3 | Lecture | 2 | Tutorial | 0 | Practical | 2 |
| Course description: | |||||||||
| This course provides the principles underlying the actions of drugs; including pharmacokinetics, drug- receptor interactions, and drug metabolism. It explores the fundamental mechanism of drug action emphasizing the modulation of interactions between endogenous ligands and targets. Key target types include receptors, enzymes, transporter proteins, ion channels and nucleic acids. Key concepts include enzyme action, regulation, inhibition and signal transduction. In addition, the course provides the basic principles of drug absorption, distribution, metabolism and excretion. It also provides the conceptual knowledge of physiology and pathophysiology of the neuromuscular and the autonomic nervous system as well as the drugs acting upon them. | |||||||||
| Course Title | Pathology | ||||||||
| Course Code | PLC 204 | Credit Hours | 2 | Lecture | 2 | Tutorial | 1 | Practical | 0 |
| Course description: | |||||||||
| The study of biochemical, structural and functional changes in cells, tissues and organs, which are caused by diseases. | |||||||||
| Course Title | Biochemistry II | ||||||||
| Course Code | PLC 205 | Credit Hours | 3 | Lecture | 2 | Tutorial | 0 | Practical | 2 |
| Course description: | |||||||||
| Mobilization of body stores of glycogen and fats -Metabolism and tissue utilization of glucose, amino acids, and fatty acids – Metabolismof lipoprotein– Regulation of blood glucose level and clinical correlations – Feed/fast cycle – Nitrogen metabolism and nitrogen balance – Inborn errors of metabolism –Oxidative stress. | |||||||||
| Course Title | Pharmacology I | ||||||||
| Course Code | PLC 301 | Credit Hours | 3 | Lecture | 2 | Tutorial | 0 | Practical | 2 |
| Course description: | |||||||||
| This course integrates principles of pharmacology with conceptual knowledge of physiology and pathophysiology to disease processes regarding, autacoids and cardiovascular systems, renal & hematology. | |||||||||
| Course Title | Pharmacology II | ||||||||
| Course Code | PLC 302 | Credit Hours | 3 | Lecture | 2 | Tutorial | 0 | Practical | 2 |
| Course description: | |||||||||
| This course integrates principles of pharmacology with conceptual knowledge of physiology and pathophysiology disease processes regarding drugs acting on central nervous system, gastro-intestinal and pulmonary systems. The anti-inflammatory, analgesics as well as gout treatments are also within the scope of the course. | |||||||||
| Course Title | First Aid and Basic Life Support (BLS) | ||||||||
| Course Code | PLC 303 | Credit Hours | 1 | Lecture | 1 | Tutorial | 1 | Practical | 0 |
| Course description: | |||||||||
| Basic life support, bleeding, shock, medical emergencies, poisoning, bones and joints, soft tissue injuries, rescue and transportation | |||||||||
| Course Title | Pharmacology III | ||||||||
| Course Code | PLC 401 | Credit Hours | 2 | Lecture | 2 | Tutorial | 1 | Practical | 0 |
| Course description: | |||||||||
| This course integrates principles of pharmacology with conceptual knowledge of physiology and pathophysiology disease processes regarding drugs acting on endocrine system. Chemotherapeutic drugs including antimicrobials, anticancer and immunosuppressant are within the scope of the course. Stem cell therapy is also included. | |||||||||
| Course Title | Clinical Biochemistry | ||||||||
| Course Code | PLC 402 | Credit Hours | 3 | Lecture | 2 | Tutorial | 0 | Practical | 2 |
| Course description: | |||||||||
| Organ function and laboratory diagnostic tests (liver – kidney – heart – pancreas – bone) – Plasma proteins and albumin/globulin ratio – Types and lab differentiation of hyperlipidemia – Examples of different diseases (case study – interpretation of analytical data) – Handling, preservation, storage and analysis of biological samples – Abnormalities of urine analysis – Blood analysis and complete blood count – Tumor markers – Endocrinology (classification of hormones – mechanisms of action – dysfunction) – Electrolytes, blood gases and acid-base balance – Recent diagnostic biomarkers. | |||||||||
| Course Title | Toxicology and Forensic Chemistry | ||||||||
| Course Code | PLC 501 | Credit Hours | 3 | Lecture | 2 | Tutorial | 0 | Practical | 2 |
| Course description: | |||||||||
| This course provides basics and concepts of toxicology including the mechanism of toxicity, target organ and treatment of toxicity. Toxic groups including heavy metals, toxic gases, animal, plant and marine poisons, pesticides and radiation hazards are covered. Environmental, occupational, reproductive and genetic toxicology as well as drug abuse are included. Postmortem sampling for detection of poisons, methods of detection, interpretation of results and writing of a report are also covered. | |||||||||
| Course Title | Clinical Nutrition | ||||||||
| Course Code | PLC 502 | Credit Hours | 2 | Lecture | 2 | Tutorial | 1 | Practical | 0 |
| Course description: | |||||||||
| The aim of the course is designed to provide the student with understanding of the fundamentals of nutrition, roles of carbohydrates, proteins, fats, water, minerals and vitamins in clinical nutrition and how these components promote and maintain of optimal health. Nutritional assessment and management of patients requiring specialized nutrition support. Nutritional therapy in specific diseases (diabetes, cardiovascular, cancer, gastrointestinal diseases, malnutrition and genetic diseases). | |||||||||
| Elective Courses | |||||||||
| Course Title | Pharmacotherapeutics for Special Population | ||||||||
| Course Code | PLC E01 | Credit Hours | 2 | Lecture | 1 | Tutorial | 2 | Practical | 0 |
| Course description: | |||||||||
| This course aimed to promote health, prevent and treat diseases in pediatric- geriatric aged group in addition to drug therapy for pregnant and lactating patients. | |||||||||
| Course Title | Geriatric Pharmacotherapy | ||||||||
| Course Code | PLC E02 | Credit Hours | 2 | Lecture | 1 | Tutorial | 2 | Practical | 0 |
| Course description: | |||||||||
| This course aimed to promote health, prevent and treat diseases in geriatric aged group, also the course deals with adverse drug reactions and interactions. In addition to management of neurological disorders in these special population. | |||||||||
| Course Title | Addiction and Drug Abuse | ||||||||
| Course Code | PLC E03 | Credit Hours | 2 | Lecture | 1 | Tutorial | 2 | Practical | 0 |
| Course description: | |||||||||
| This course deals with the socio-psychological, biological, genetic and pharmacological aspects of the problem and strategies for prevention and treatment. | |||||||||
| Course Title | Molecular Therapeutics | ||||||||
| Course Code | PLC E04 | Credit Hours | 2 | Lecture | 1 | Tutorial | 2 | Practical | 0 |
| Course description: | |||||||||
| This course involves a wide range of new molecular therapies such as simple protein replacement therapy, gene augmentation therapy, antisense therapy, stem cells therapy and advanced therapies of cancer. It focuses on the new in the clinical trials of stem cell therapy that considered one of the important types of future medicine. Also, it provides knowledgeabout the advanced molecular diagnosis and therapy of cancer. | |||||||||